Below are the steps to do this
1) Encrypt appsettings in web.config using Aspnet_regiis.exe
using Aspnet_regiis.exe you can encrypt whole section only not a particular key.so when you need to encrypt a particular key in appSettings things get complicated. Here is a roundabout way of doing this. Modify your web.config
Also secureAppSettings is the name i had given. You can give any. Save this web.config file and go to visual studio command prompt
3) Type
aspnet_regiis -pef secureAppSettings “ur web.config path” -prov DataProtectionConfigurationProvider
4) In code you can access it as usual
NameValueCollection secureAppSettings = (NameValueCollection)ConfigurationManager.GetSection("secureAppSettings")
String str= secureAppSettings["ipwd"];
For example to decrypt identity section